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目的:研究胸腔镜下肺叶切除术联合淋巴结清扫术治疗肺癌的临床效果,为该类疾病的治疗提供依据。方法:对2010年5月至2014年12月我院入院治疗的142例肺癌患者进行了研究,随机分为两组(每组71例),对照组采用开放手术方式,观察组采用胸腔镜手术方式。比较两组患者围手术期情况,包括淋巴结清扫个数、手术出血量等参数,比较两组患者手术后不同时间点的疼痛评分,最后比较两组患者围手术期并发症的发生情况。结果:两组患者淋巴结清扫个数与手术时间基本相当,观察组患者的手术出血量、术后引流时间以及住院时间明显低于对照组,两组间比较差异明显(P<0.05);观察组患者在术后1 d、术后3 d和术后5 d的疼痛评分均明显低于对照组,差异有统计学意义(P<0.05);观察组患者肺部感染、持续漏气、肺不张等并发症的发生率均明显低于对照组,两组间比较差异有统计学意义(P<0.05)。结论:胸腔镜下肺叶切除术联合淋巴结清扫术治疗肺癌临床效果显著,可以明显的减少手术出血量及住院时间,并且镇痛效果更好,肺部感染、肺不张等并发症的发生率更低,值得临床推广应用。
Objective: To study the clinical effect of thoracoscopic lobectomy combined with lymphadenectomy in the treatment of lung cancer and provide the basis for the treatment of such diseases. Methods: A total of 142 patients with lung cancer undergoing hospital admission from May 2010 to December 2014 in our hospital were randomly divided into two groups (71 in each group). The control group was treated by open surgery. The patients in the observation group were treated by thoracoscope the way. Perioperative conditions were compared between the two groups, including the number of lymph node dissection, the amount of bleeding and other parameters. The pain score was compared between the two groups at different time points after surgery. Finally, the incidence of perioperative complications was compared between the two groups. Results: The number of lymph node dissection in both groups was basically the same as the operation time. The bleeding volume, postoperative drainage time and hospital stay in the observation group were significantly lower than those in the control group (P <0.05). The observation group The pain scores of the patients at 1 day after operation, 3 days after operation and 5 days after operation were significantly lower than those in the control group (P <0.05). In the observation group, pulmonary infection, persistent air leak and lung failure Zhang and other complications were significantly lower than the control group, the difference between the two groups was statistically significant (P <0.05). Conclusions: Thoracoscopic lobectomy combined with lymphadenectomy for the treatment of lung cancer has significant clinical effect, which can significantly reduce the amount of surgical bleeding and hospital stay, and the analgesic effect is better. The incidence of complications such as pulmonary infection and atelectasis is even more Low, it is worth to promote clinical application.