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目的:评价国产和进口阿卡波糖片治疗Ⅱ型糖尿病效果和成本。方法:选取2015年1月至2016年1月广州市越秀区洪桥街社区卫生服务中心收治的106例Ⅱ型糖尿病患者,按随机数字表法分为观察组和对照组,每组53例分别予以国产阿卡波糖和进口阿卡波糖治疗,比较两组患者治疗后血糖指标、不良反应发生率、临床疗效、治疗成本。结果:两组患者治疗后餐后2 h血糖(2 h PPG)、糖化血红蛋白(HbAlc)均比治疗前下降,差异具有统计学意义(P<0.05),空腹C肽(CP)、餐后2 h C肽(2 h CP)比治疗前升高,差异具有统计学意义(P<0.05),治疗后两组患者血糖指标比较差异无统计学意义(P>0.05),两组患者总有效率、不良反应发生率比较,差异无统计学意义(P>0.05),对照组C/E值高于观察组,差异具有统计学意义(P<0.05),两组患者?C/?E为114.6。结论:国产与进口阿卡波糖片治疗Ⅱ型糖尿病临床效果相似,国产阿卡波糖有经济上的优势。
OBJECTIVE: To evaluate the efficacy and cost of domestic and imported acarbose in the treatment of type 2 diabetes. Methods: From January 2015 to January 2016, 106 patients with type 2 diabetes admitted to Hongqiao Street Community Health Service Center in Yuexiu District of Guangzhou City were randomly divided into observation group and control group, with 53 cases in each group Domestic acarbose and imported acarbose treatment, comparison of two groups of patients after treatment, blood glucose, adverse reactions, clinical efficacy, treatment costs. Results: The levels of 2 h PPG and HbAlc in both groups after treatment were significantly lower than those before treatment (P <0.05). The levels of fasting C-peptide (CP), postprandial 2 h C peptide (2 h CP) was higher than that before treatment, the difference was statistically significant (P <0.05). There was no significant difference in blood glucose between the two groups after treatment (P> 0.05). The total effective rate (P> 0.05). The C / E of the control group was higher than that of the observation group (P <0.05), and the C / E of the two groups was 114.6 . Conclusion: Domestic and imported acarbose treatment of type Ⅱ diabetes clinical effect is similar to domestic acarbose with economic advantages.