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氨苯(口派)啶醇(AG)可抑制肾上腺碳链裂解酶,从而阻止胆固醇转化成孕烯醇酮,并通过抑制外周循环中的芳香酶阻止雄性激素转变成雌激素。因此,常用AG治疗乳癌病人。本实验的目的是确定AG加用氢化考地松(HC)是否对绝经后乳癌患者雌激素水平有影响。受试患者均已绝经,且4周内末曾接受过内分泌治疗。23名患者接受AG125mg,每日二次。其平均年龄61.2±2.1(45～82岁),体重66.0±2.3kg(52
Aminobenzenes (Mouth) The alcohol (AG) inhibits the adrenal carbon chain cleavage enzyme, thereby preventing the conversion of cholesterol to pregnenolone, and prevents the androgen from turning the male hormone into estrogen by inhibiting the circulating aromatase. Therefore, commonly used AG treatment of breast cancer patients. The purpose of this experiment was to determine if AG plus hydrocortisone (HC) had an effect on estrogen levels in postmenopausal women with breast cancer. All patients tested had been menopausal and had received endocrine therapy at the end of 4 weeks. Twenty-three patients received AG 125 mg twice daily. The average age of 61.2 ± 2.1 (45 ~ 82 years old), body weight 66.0 ± 2.3kg (52