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传统观念很顽固,系统性红斑狼疮(简称SLE)一经诊断,总常引起一系列医学上的反应,包括大剂量皮质激素治疗,劝告绝育,并想到肾炎是必然的后果和不良的预后。在过去的20年期间,由于敏感性高的抗核抗体试验的开展,使人们认识到SLE远较过去想象的要常见,而且大多数病例病情亦较轻。据目前统计资料表明,在妇女中发病率达到1∶2000。在某些人群,如美国、西印度群岛和南非的黑人妇女,发病率可高达1∶250,
The traditional concept is very stubborn. Once diagnosed, systemic lupus erythematosus (SLE) often causes a series of medical reactions, including high-dose corticosteroid therapy, advising on sterilization and relying on nephritis as a necessary consequence and a poor prognosis. During the past two decades, the development of highly sensitive antinuclear antibody tests has led to the recognition that SLE is more common than previously thought and most cases are less benign. According to the current statistics, the incidence in women reached 1: 2000. In some populations, such as black women in the United States, the West Indies and South Africa, the incidence can be as high as 1: 250,