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目的了解糖尿病(DM)病人血清果糖胺(FMN)与血糖之间的关系及临床意义。方法对90例DM患者及79例正常对照组分别进行血清FMN,空腹血糖(FBG)测定,并对DM患者的餐后2 h血糖和FMN进行测定。结果 DM患者空腹及餐后2 h的FMN与正常对照组比较差异有统计学意义(P<0.01),而患者空腹和餐后2 hFMN差异无统计学意义(P>0.05);DM患者血清FMN与血糖之间呈正相关(r=0.55,P<0.01)。结论 FMN与血糖的关系密切,2者的联合检测对糖尿病的诊断和疗效的判断具有重要的临床意义。
Objective To investigate the relationship between serum fructosamine (FMN) and blood glucose in patients with diabetes mellitus (DM) and its clinical significance. Methods Serum FMN and fasting plasma glucose (FBG) were measured in 90 DM patients and 79 normal controls respectively. The postprandial blood glucose and FMN 2 h were measured in DM patients. Results The FMN of fasting and postprandial 2-h DM patients was significantly lower than that of normal controls (P <0.01), but there was no significant difference between fasting and postprandial 2-h FMN (P> 0.05) And blood glucose was positively correlated (r = 0.55, P <0.01). Conclusion FMN is closely related to blood glucose. The combined detection of 2 and 2 has important clinical significance in the diagnosis and treatment of diabetes.