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为了探讨肿瘤血管生成与喉癌颈淋巴结转移关系的意义，应用ＣＤ３４单克隆抗体，以免疫组织化学法，通过ＣＤ３４单克隆抗体标记血管内皮对５８例喉鳞状细胞癌组织中微血管计数。结果：３０例颈淋巴结转移组平均微血管密度为４１．４４±１６．９４个／２００×，２８例非转移平均微血管密度为１９．７４±１０．１１个／２００×，及９例正常喉组织平均微血管密度为９．１４±３．８７个／２００×。３组间有显著差异（Ｐ＜０．０１），瘤内微血管密度与颈淋巴结转移有明显正相关性。认为喉鳞状细胞癌微血管定量与颈淋巴结转移有重要意义，可预测颈淋巴结转移的危险性，可作为喉鳞状细胞癌预后的一个重要指标。
In order to explore the significance of the relationship between tumor angiogenesis and cervical lymph node metastasis of laryngeal carcinoma, CD34 monoclonal antibody was used to detect the microvessel count in 58 cases of laryngeal squamous cell carcinoma with CD34 monoclonal antibody by immunohistochemistry. Results: The average microvessel density was 41.44 ± 16.94 / 200 × in 30 cases of cervical lymph node metastasis, 28 cases of non-metastasis average microvessel density was 19.74 ± 10.11 / 200 ×, and 9 cases of normal laryngeal tissue The mean microvessel density was 9.14 ± 3.87 / 200 ×. There were significant differences among the three groups (P <0.01), and there was a significant positive correlation between the microvessel density and cervical lymph node metastasis. Laryngeal squamous cell carcinoma microvessel volume and cervical lymph node metastasis is important, can predict the risk of cervical lymph node metastasis, can be used as an important indicator of the prognosis of laryngeal squamous cell carcinoma.