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谷胱甘肽S转移酶 (GST)是一个Ⅱ相药物代谢酶的超家族 ,是细胞抗损伤、抗癌变的重要解毒系统 ,其中GSTπ表达水平的改变可能与化疗耐药有关[1 ,2 ] 。目前有关健康人群和白血病患者的GSTπ活性范围、两群体间的差异以及GSTπ活性与白血病的相关性尚无报道。我们采用ELISA方法检
Glutathione S-transferase (GST) is a superfamily of phase II drug-metabolizing enzymes that is an important detoxification system for cell injury and anti-cancer. The change of GSTπ expression may be related to chemoresistance [1,2 ]. At present, there is no report about the range of GSTπ activity, the difference between two groups and the correlation between GSTπ activity and leukemia in healthy and leukemia patients. We use ELISA method