论文部分内容阅读
1969年Berger首先描述了一种在肾小球系膜区有IgA和IgG、C_3沉积的肾小球肾病,其典型病例为无症状性镜下血尿,常伴有蛋白尿和/或发作性肉眼血尿。多见于男性、学龄儿和青年。早先报道资料认为,此病预后良好,而近年资料表明有些病人经过数年至数十年后,肾功能慢性衰退。方法及诊断标准作者15年中进行肾活检819例,其中5例病理和临床表现符合以下标准而确定为急进性IgA肾病,即:(1)肾小球系膜区有IgA和C_3沉积,可伴有或不伴有IgG或IgM沉积;(2)40%以上肾小球有新月体形成或肾小球荒废;(3)无全身
In 1969 Berger first described a glomerular nephropathy with IgA and IgG, C_3 deposition in the mesangial area, a typical case of asymptomatic microscopic hematuria, often associated with proteinuria and / hematuria. More common in men, school-age children and youth. Earlier reported data that the prognosis of the disease is good, and recent years show that some patients after several years to decades after chronic renal failure. Methods and Diagnostic Criteria The authors performed 819 renal biopsy tests in 15 years, of which 5 were pathologically and clinically confirmed as acute IgA nephropathy, namely: (1) IgA and C_3 deposits in the mesangial area, and With or without IgG or IgM deposition; (2) more than 40% of glomeruli with crescent or glomerular obstruction; (3) without systemic