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对本院35a来经病理证实的38例小儿肝炎后肝硬化进行了回顾性研究。病例年龄2个月至14岁,平均6.0(±4.2)岁,小于1岁者占18.4%。男女之比为1.4:1。在肝穿刺证实的小儿慢性肝病中占11.5%,在小儿尸解病例中占0.4%。1例有急性乙肝病史患儿,发病5个月肝穿刺证实为早期肝硬化。肝脾肿大突出,但无早期诊断意义。血免疫球蛋白明显升高,补体C3普遍降低。血清乙肝病毒标记物(HBVM)总阳性率72.2%。可见小儿肝炎后肝硬化并不少见,且发病早、发展快,主要为乙肝后肝硬化。
A retrospective study of 38 pediatric posthepatitic cirrhosis confirmed by pathology in our hospital 35 years old was conducted. The patients were from 2 months to 14 years old, with an average of 6.0 (± 4.2) years old and 18.4% younger than 1 year old. The ratio of male to female is 1.4: 1. 11.5% of children with chronic liver disease confirmed by liver biopsy and 0.4% of children with autopsy. One patient had a history of acute hepatitis B and 5 months of onset of liver biopsy confirmed early cirrhosis. Hepatosplenomegaly prominent, but no early diagnostic significance. Blood immunoglobulin was significantly elevated, complement C3 generally lower. The total positive rate of serum HBV markers (HBVM) was 72.2%. Can be seen in children with cirrhosis of liver is not uncommon, and the incidence of early, rapid development, mainly for hepatitis B cirrhosis.