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目的研究阿奇霉素与布地奈德雾化吸入联合治疗小儿肺炎支原体肺炎的临床效果及不良反应。方法将我院2010年3月-2012年3月收诊的72例小儿支原体肺炎患者随机分成两组各36例,对照组给予阿奇霉素治疗,观察组在对照组基础上雾化吸入布地奈德联合治疗,3周后比较两组临床效果。结果两组患儿经治疗后,观察组总有效率94.44%显著高于对照组77.78%(P<0.05),发热、咳嗽消失时间及平均住院时间也明显少于对照组(P<0.01),两组患者阿奇霉素治疗时分别有3例和2例发生腹泻、腹痛、呕吐等症状,不良反应率比较无统计学意义(P>0.05)。结论阿奇霉素与雾化吸入布地奈德联合治疗小儿肺炎支原体肺炎,可有效减轻患者咳嗽、发热等症状,缩短住院时间,临床效果好,值得推广应用。
Objective To study the clinical effects and adverse reactions of azithromycin combined with budesonide inhalation in the treatment of children with Mycoplasma pneumoniae pneumonia. Methods Seventy-two children with Mycoplasma pneumoniae pneumonia admitted to our hospital from March 2010 to March 2012 were randomly divided into two groups of 36 cases each. The control group was treated with azithromycin. The observation group was treated with inhalation of budesonide After 3 weeks of treatment, the clinical effects of the two groups were compared. Results After treatment, the total effective rate in the observation group was 94.44%, significantly higher than that in the control group (77.78%, P <0.05). The incidence of fever, disappearance of cough and average length of stay in the two groups were also significantly less than those in the control group (P <0.01) Two cases of azithromycin treatment were 3 cases and 2 cases of diarrhea, abdominal pain, vomiting and other symptoms, the adverse reaction rate was not statistically significant (P> 0.05). Conclusion Azithromycin and inhaled budesonide combined treatment of children with Mycoplasma pneumoniae pneumonia, can effectively reduce symptoms such as cough, fever and other patients, shorten the hospital stay, the clinical effect is good, it is worth promoting the application.