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目的在6种不同商用放射治疗计划系统(TPS)间传递一组患者数据,比较计算出的感兴趣区域(ROI)体积值,研究分析传递导致的变化趋势和程度。方法 2010年10月-2013年12月,将四川大学华西医院临床治疗的10例鼻咽癌患者数据,从Monaco TPS导入各计划系统,分别读取各个ROI的体积值,按照体积大小分为8组。分组计算相对于Monaco TPS的体积差异,进行统计分析。结果对于小体积的ROI,不同TPS中计算得到的体积值差异可达65%;整体是ROI的体积越大相对差异越小。但对于每一个单个的ROI,其体积值的差异变化似乎是随机的。Raystation TPS中70%、Pinnacle TPS中38.75%、Eclipse TPS中88.75%、Masterplan TPS中97.5%、i Plan TPS中83.13%的ROI体积比Monaco TPS中的值小。结论采用医学数字成像和通信协议传输ROI体积在不同系统中不同计算值的现象是普遍存在的。在两个不同系统间进行直接的剂量体积直方图比较之前,应该先评估ROI体积的一致性。
Objective To transmit a set of patient data between six different commercial radiotherapy planning systems (TPS), compare calculated volume of ROI values, and analyze the trends and extent of transmission-induced changes. Methods From October 2010 to December 2013, 10 cases of nasopharyngeal carcinoma patients treated clinically in West China Hospital of Sichuan University were imported from Monaco TPS into each planning system. The volumes of each ROI were read and divided into 8 group. Grouping calculated volume differences relative to Monaco TPS for statistical analysis. Results For a small volume of ROI, the difference between the volume values calculated in different TPS can reach 65%; the overall is that the larger the volume of ROI is, the smaller the relative difference is. But for each individual ROI, the variance in volume values seems to be random. 70% in the Raystation TPS, 38.75% in the Pinnacle TPS, 88.75% in the Eclipse TPS and 97.5% in the Masterplan TPS. 83.13% of the ROI volume in the i Plan TPS is smaller than in the Monaco TPS. CONCLUSIONS It is ubiquitous to use medical digital imaging and communication protocols to transmit ROI volumes to different calculated values in different systems. Before direct dose-volume histogram comparison between two different systems, one should first assess the consistency of the ROI volume.