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目的:观察瑞芬太尼联合丙泊酚用于无痛人工流产术麻醉中的可行性和安全性,并与单独使用丙泊酚行无病人工流产术麻醉进行比较。方法:选择门诊I一Ⅱ级早期妊娠需无痛人工流产术者200例,随机分成两组,每组100例,丙泊酚组(P组):丙泊酚2.5mg/kg持续静脉滴注60S,必要时追加丙泊酚0.5～1.0mg/kg;瑞芬太尼+丙泊酚组(RP组):静脉推注瑞芬太尼1.0ug/kg、丙泊酚1mg/kg持续静脉推注60S,随后静脉泵入瑞芬太尼0.1ug/kg/min。结果:两组患者对镇痛效果满意,RP组苏醒时间短于P组,RP组体动反应、术中低血压发生少于P组,两组比较差异有统计学意义(P<0.05)。结论:瑞芬太尼联合丙泊酚用于无痛人工流产术,麻醉效果满意,不良反应少。
Objective: To observe the feasibility and safety of remifentanil combined with propofol in anesthesia induced by painless artificial abortion, and to compare with the anesthesia of free abortion without propofol alone. Methods: 200 outpatients with grade Ⅰ-Ⅱ early pregnancy requiring painless abortion were randomly divided into two groups, 100 in each group, propofol group (P group): propofol 2.5mg / kg continuous intravenous infusion 60S, propofol 0.5 ~ 1.0mg / kg if necessary; remifentanil + propofol group (RP group): intravenous remifentanil 1.0ug / kg, propofol 1mg / kg sustained intravenous push Note 60S followed by intravenous infusion of remifentanil at 0.1 ug / kg / min. Results: The analgesic effect was satisfactory in both groups. The recovery time in RP group was shorter than that in P group. The body motion response in RP group was less than that in P group. There was significant difference between the two groups (P <0.05). Conclusion: Remifentanil combined with propofol for painless artificial abortion has satisfactory anesthetic effect and few adverse reactions.