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目的探讨和研究重度子痫前期合并胎儿宫内生长受限,其发病因素与病人年龄、居住环境、饮食习惯和是否正规孕期保健的关系;与终止妊娠时机和新生儿预后的关系。方法回顾性总结2012年9月至2015年5月昌黎县人民医院产科收治有详尽病史资料的重度子痫前期合并胎儿宫内生长受限的28例病例进行回顾性分析,入院时对病人详尽查体,仔细询问病史,同时就病人平时的居住环境饮食习惯及是否进行正规产前检查进行登记整理。完善相关的如胎儿B超等辅助检查,产后新生儿的即时随访,确诊为重度子痫前期合并胎儿宫内生长受限。分析:1.发病年龄同该病的关系;2.发病与病人居住,饮食习惯和是否正规孕期检查的关系。3.积极解痉降压同时干预治疗胎儿宫内生长受限,予以氟美松肌注促胎肺成熟的孕周、结束妊娠的时机与新生儿预后的关系。结果 1.年龄过大过小是重度子痫前期合并胎儿宫内生长受限发病存在明显关系P<0.05,具有统计学意义。2.居住环境差,饮食不规律,平时喜油腻饮食,营养不均衡且无正规产前检查是发病的主要因素。3.结束妊娠孕周与新生儿预后有明显关系,P<0.05,具有统计学意义。结论适龄怀孕,良好的居住环境,均衡合理饮食及正规的产前检查,可以降低重度子痫前期合并胎儿宫内生长受限的发病率,适当延迟孕周和早期诊断及孕期积极干预治疗可以明显提高新生儿成活率。
Objective To investigate and study the relationship between fetal growth restriction and severe preeclampsia, the relationship between the risk factors and patient’s age, living environment, eating habits and regular pregnancy health, and the relationship between the timing of termination of pregnancy and the prognosis of newborns. Methods From September 2012 to May 2015, 28 cases of severe preeclampsia with limited fetal growth admitted to obstetrics and gynecology in Changli County People’s Hospital were retrospectively reviewed. The patients were exhaustively surveyed on admission Body, carefully asked about the history, at the same time the patient’s usual living environment, eating habits and whether to conduct regular prenatal check registration. Improve the related such as fetus B ultrasound and other auxiliary examination, immediate follow-up of postpartum newborns, diagnosed as severe preeclampsia with fetal growth restriction. Analysis: 1. The age of onset with the disease; 2. The incidence and the patient’s living, eating habits and whether the regular pregnancy check the relationship. 3. Positive spasm antihypertensive intervention at the same time the treatment of fetal growth restriction, to give Fomeisan injection of fetal lung maturity gestational age, the timing of termination of pregnancy and the relationship between the prognosis of newborns. Results 1. Excessive age is too severe preeclampsia with intrauterine growth restriction incidence of significant correlation P <0.05, with statistical significance. 2. Poor living environment, irregular diet, like hi greasy diet, nutritional imbalance and no formal prenatal examination is the main factor in the incidence. 3. End pregnancy gestational age and neonatal prognosis have a significant relationship, P <0.05, with statistical significance. Conclusion Proper pregnancy, good living environment, balanced and reasonable diet and regular prenatal examination can reduce the incidence of severe fetal preeclampsia with limited fetal growth restriction. Proper gestational weeks and early diagnosis and active intervention during pregnancy can be significantly reduced Improve newborn survival rate.