论文部分内容阅读
恶性葡萄胎与绒毛膜上皮细胞癌(以下简称恶葡与绒癌)在未用化学药物治疗前死亡率较高。自从氮芥问世28年来,抗癌药物不断进展,使本病的预后有了明显改善。近几年对细胞动力学的研究,为合理用药提供了理论基础,为了提高治疗效果,兹就常用治疗本症药物加以综述。一、烷化剂组:为一些具有二个或二个以上活性基团的化合物,其碳氢键中的原子很容易释出,可与许多代谢上重要的基团结合,以烃基取代这些生物基质的氯原于,使之不能从通常方式在细胞代
Malignant hydatidiform mole and choriocarcinoma (hereinafter referred to as cesarean and choriocarcinoma) higher mortality rate before treatment with chemical drugs. Since the advent of nitrogen mustard 28 years ago, anti-cancer drugs continue to progress, so that the prognosis of the disease has been significantly improved. In recent years, the study of cell kinetics provides a theoretical basis for rational drug use, in order to improve the therapeutic effect, it is commonly used to treat the disease drug to be reviewed. First, the alkylating agent group: for some compounds with two or more active groups, the carbon-hydrogen bond atoms are easily released, with a number of metabolically important groups, the hydrocarbon group to replace these organisms The stroma of chloroplast is so that it can not be taken from the cell in the usual way