Gd-DTPA对鼻咽癌诊断的价值

• 作 者: 李建军 王兆熊 李岩 韦雄 李长青
• 机 构: 海南省人民医院放射科
• 出 处: 临床放射学杂志
• 发表日期: 1997年04期
• 关键词: 鼻咽癌诊断 Gd-DTPA 鼻咽肿瘤 造影剂 鉴别诊断 有显著性差异 咽颅底筋膜 磁共振成像 放射性脑病 鼻咽部

目的：分析ＧｄＤＴＰＡ对鼻咽癌诊断的价值。材料与方法：４０例鼻咽癌患者行ＧｄＤＴＰＡ增强前后ＭＲＩ检查，其中放疗前１８例，放疗后局部复发（ＲＮＰＣ）２２例；对照组包括放疗后纤维化（ＲＦ）６例和炎性病灶２例。结果：ＧｄＤＴＰＡ增强ＭＲ检查能清晰显示鼻咽癌的侵犯范围和边界；ＲＮＰＣ与ＲＦ病灶增强后信号强度有显著性差异（Ｐ＜０．０１）；病灶无强化，可除外ＲＮＰＣ，有强化则不一定是ＲＮＰＣ，炎性病灶可有明显强化。结论：ＧｄＤＴＰＡ增强ＭＲ检查对鼻咽癌较小病灶的显示及其边界的确定优于ＭＲ平扫，且对ＲＮＰＣ的鉴别诊断具有重要价值

Objective: To analyze the value of GdDTPA in the diagnosis of nasopharyngeal carcinoma. MATERIAL AND METHODS: Forty patients with nasopharyngeal carcinoma underwent MRI examination before and after GdDTPA enhancement. Among them, 18 cases were radiotherapy before radiotherapy and 22 cases were local recurrence after radiotherapy (RNPC). The control group included 6 cases of postradiation fibrosis (RF) and inflammatory 2 cases of lesions. Results: Gd  DTPA enhanced MR examination can clearly show the scope and boundary of the invasion of nasopharyngeal carcinoma; RNPC and RF lesions enhanced signal intensity was significantly different (P <0.01); no enhancement of the lesions, except RNPC, with enhanced It is not necessarily RNPC, inflammatory lesions can be significantly enhanced. Conclusion: Gd  DTPA enhanced MR examination of nasopharyngeal lesions smaller lesions and the determination of the border is better than the MR scan, and the differential diagnosis of RNPC has important value