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本文采用单核取代法［１］，在７２１分光光度计上分别测定了镧─α─生物素与钙─α─生物素络合物体系的光密度变化，从而解析出镧─α─生物素的稳定常数β１＝３．２９×１０４；β２＝１．６０×１０７。而钙─α─生物素的稳定常数β１＝５．１０×１０２；β２＝２．５８×１０６．可见前者比后者的稳定常数要大二个数量级，这说明稀土镧可与人体大量摄入的α─生物素络合，不会在人体中积累，也不可能竞争取代人体中的钙。从而在理论的一个方面证明稀土微肥是低毒无害的。
In this paper, the mononuclear substitution method [1] was used to determine the optical density changes of lanthanum-α-biotin and calcium-α-biotin complex system on a 721 spectrophotometer, The stability constant β1 = 3.29 × 104; β2 = 1.60 × 107. Calcium ─ α-biotin stability constant β1 = 5.10 × 102; β2 = 2.58 × 106. It can be seen that the former is two orders of magnitude larger than the latter, indicating that lanthanum lanthanum complexes with α-biotin, which is ingested by the body in large quantities, and will not accumulate in the human body or compete with calcium in the human body. Thus in one aspect of theory that rare earth fertilizer is low toxicity harmless.