论文部分内容阅读
内脂素/前B细胞克隆增强因子(visfatin/PBEF)作为新发现的脂肪因子,主要在内脏脂肪和大网膜中表达,具有类胰岛素作用、参与炎症反应和免疫调节等功能。妊娠期妇女处于特殊的生理状态,能量代谢发生特征性改变。最新观点认为妊娠合并症,如妊娠期糖尿病和妊娠期高血压疾病均存在胰岛素抵抗,是妊娠妇女体内代谢功能紊乱所致。近年对visfatin/PBEF的结构和功能、其与代谢综合征、子痫前期、妊娠期糖尿病和胎儿生长受限关系的研究提示,visfatin/PBEF可能参与妊娠相关疾病的发生和发展。就近年关于vis-fatin/PBEF和妊娠合并症的相关研究综述。
As a newly discovered adipokine, visfatin / PBEF is mainly expressed in visceral fat and omentum, has the function of insulin-like, and is involved in inflammation reaction and immune regulation. Pregnant women in a special physiological state, energy metabolism occurs characteristic changes. The latest point of view that pregnancy complications, such as gestational diabetes and gestational hypertension are insulin resistance, metabolic disorders in pregnant women due to the body. In recent years, visfatin / PBEF structure and function, its relationship with metabolic syndrome, preeclampsia, gestational diabetes and fetal growth restriction suggest that visfatin / PBEF may be involved in the occurrence and development of pregnancy-related diseases. In recent years, on vis-fatin / PBEF and pregnancy complications related research review.