【摘 要】
：
Background:Regular physical activity (PA) has been postulated to improve,or at least maintain,immunity across the life span.However,the link between physical (in)activity and coronavirus disease 2019 (COVID-19) remains to be established.This small-scale p
【机 构】
：
Applied Physiology and Nutrition Research Group,School of Physical Education and Sport,Clinical Hosp
论文部分内容阅读
Background:Regular physical activity (PA) has been postulated to improve,or at least maintain,immunity across the life span.However,the link between physical (in)activity and coronavirus disease 2019 (COVID-19) remains to be established.This small-scale prospective cohort study is nested within a randomized controlled trial aimed to investigate the possible associations between PA levels and clinical outcomes among hospitalized patients with moderate to severe COVID-19.Methods:Hospitalized patients with COVID-19 (mean age:54.9 years) were recruited from the Clinical Hospital of the School of Medicine of the University of Sao Paulo (a quatemary referral teaching hospital) and from Ibirapuera Field Hospital,both located in Sao Paulo,Brazil.PA level was assessed using the Baecke Questionnaire of Habitual Physical Activity.The primary outcome was hospital length of stay.The second-ary outcomes were mortality,admission to the intensive care unit (ICU),and mechanical ventilation requirement.Results:The median hospital length of stay was 7.0 ± 4.0 days,median ± IQR;3.3％ of patients died,13.8％ were admitted to the ICU,and 8.6％required mechanical ventilation.Adjusted linear regression models showed that PA indices were not associated with hospital length of stay(work index:β =-0.57 (95％ confidence interval (95％CI):-1.80 to 0.65),p =0.355;sport index:β =0.43 (95％CI:-0.94 to 1.80),p =0.536;leisure-time index:β =1.18 (95％CI:-0.22 to 2.59),p =0.099;and total activity index:β =0.20 (95％CI:-0.48 to 0.87),p =0.563).None of the PA indices were associated with mortality,admission to the ICU,or mechanical ventilation requirement (all p ＞ 0.050).Conclusion:Among hospitalized patients with COVID-19,PA did not independently associate with hospital length of stay or any other clinically rele-vant outcomes.These findings should be interpreted as meaning that,among already hospitalized patients with more severe forms of COVID-19,being active is a potential protective factor likely outweighed by a cluster of comorbidities (e.g.,type 2 diabetes,hypertension,weight excess) and older age,suggesting that the benefit of PA against the worsening of COVID-19 may vary across stages of the disease.
其他文献
通过核心用人企业、行业等社会各个利益相关方调研,确定了建筑工程技术专业的教育目标,细化专业教育目标为本专业学生毕业应达到的毕业要求,将毕业要求结合专业工作过程,凝练为在教学过程中可实施培养锻炼的六项专业核心技能,将核心技能分解到各个学期对应的课程中,循序渐进培养,形成本专业核心技能形成路径,通过学校课程诊改平台、核心技能通过率、专业综合实作课程的实施,评价学生专业核心能力达成情况.
With the rising incidence of cardiovascular diseases,the concomitant mortality and morbidity impose huge burdens on quality of life and societal costs.It is generally accepted that physical inactivity is one of the major risk factors for cardiac disease a
Growing evidence has demonstrated exercise as an effective way to promote cardiovascular health and protect against cardiovascular diseases However,the underlying mechanisms of the beneficial effects of exercise have yet to be elucidated.Animal exercise s
Background:Cardiorespiratory fitness (CRF) is inversely associated with mortality in apparently healthy subjects and in some clinical popula-tions,but evidence for the association between CRF and all-cause and/or cardiovascular disease (CVD) mortality in
Purpose:The objective of this scoping review was to summarize systematically the available literature investigating the relationships between the coronavirus disease 2019 (COVID-19) pandemic and movement behaviors (physical activity,sedentary behavior,and
习近平总书记在中国共产党成立一百周年庆祝大会上,总结了中国共产党百年波澜壮阔的伟大历程,自始至终体现出为中国人民谋幸福、为中华民族谋复兴的初心使命.在不同历史时期,中国共产党以“人”的不同视域框定革命对象和工作重心,并通过党的政治力、组织力和牺牲精神给予全面有效落实,充分彰显了中国共产党殷殷为民情怀和“大我无我”高尚境界.
教育对中华民族伟大复兴具有决定性意义,对经济社会发展、确立和维持强国地位起着巨大作用.德育教育对大学生健康成长成才和高校全面工作具有重要导向和保证作用.进入新时代,高校德育教育面临新的挑战,如何找到适应新常态的德育教育方法、有效提高德育教育成效、全面培养德才兼备的新时代青年,已成为高校思想政治工作的紧迫任务.把生态学概念引入高等教育领域,树立新型生态理念和生态观,用可持续发展观点研究高校德育生态系统建设,用新发展理念定位新时代高校德育发展路径,让高校“立德树人”根本任务能够落到实处.
文化产业的发展始终同科技创新紧密融合、相辅相成.数字技术与数字经济飞速发展,为加快文化产业供给侧结构性改革,实现高质量发展开辟了广阔空间.文章在总结近年来云南数字文化产业发展现状基础上,分析了存在的主要问题,提出了实现云南数字文化产业高质量发展的路径及相关建议.
“产、政、学、研”协同创新是近年来高校建设与发展的重要路径之一,产教融合、校企合作更是应用型本科高校提升教学与科研能力的主流方向.应用型本科高校作为近年来新兴的办学模式,既要承袭传统高校的精髓,又要兼顾自身的特点探讨独具内核的发展模式.文章从产教融合的背景出发分析应用型本科高校科研管理的优化对策,从管理理念、管理制度、人员素养、监督和考评机制等方面探讨了符合学校和经济社会发展的科研管理路径.
粤港澳大湾区要实现产业、经济、文化、社会协同发展,关键是粤、港、澳三地科技要协同创新,力争打造享誉世界的国际科技创新中心.文章首先对协同创新理论进行梳理,在文献回顾的基础上整合相关理论,其次分析粤港澳大湾区协同创新的优劣势,找出存在的障碍.最后提出实现构建粤港澳大湾区协同创新机制的路径.