在用人绝经期促性腺激素的妊娠周期中黄体中期血浆孕酮的浓度

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为了解黄体中期血浆孕酮浓度与妊娠结果的关系,作者对192位不孕妇女用hMG诱导促排卵后妊娠周期的黄体中或血浆孕酮水平进行回顾性分析。192个妊娠周期中,56个周期(29.2%)结果流产,14个周期(7.3%)结果早产,2个周期间%)结果为异位妊娠,120个周期(62.5%)最后足月妊娠,其中72例单胎妊娠,48例多胎妊娠,均由hMG诱发排卵而妊娠,在病人自发或诱发月经周期的第5天起给hMG15OU肌肉注射,每天一次,腹部或阴道超声监测卵泡发育,当有一个或几个卵泡直径>18mm时肌肉注射hCGS000U,在肌肉注射hCG前进行性交试验。按Insler等的方法进行宫颈粘液评分,并根据Swyer的评定方祛观察高倍视野中活动精子数,患者均不给使用黄体酮,在给hCG7天抽肘静脉血测定血浆孕酮浓度。结果:在用hMG和hCG500OU诱导排卵的192例妊娠妇女中,黄体中期平均血浆孕酮浓度为29.O7ng/ml,足月单船妊娠为25·85us/ml,足月多胎妊娠为31.49ng/ml,流产为2864ng/ml,异位妊娠为ZI.54ng/ml,早产分娩为41.39ng/ml(9/14为多胎),在足月分娩和流产周期无显著差异,而在单胎妊娠和多服妊娠周期中有显著差异。P<0.5。作者认为黄体中期测定血浆孕酮浓度是测定排卵和黄体功能最好的有效方法之一。测定排卵的其他方? In order to understand the relationship between the mid-luteal plasma progesterone concentration and pregnancy outcome, the author retrospectively analyzed 192 cases of infertile women using hMG-induced pregnancy luteal phase or plasma progesterone level after ovulation induction. Out of 192 pregnancies, 56 cycles (29.2%) resulted in abortion, 14 cycles (7.3%) were premature, and 2 weeks resulted in ectopic pregnancy with 120 cycles (62.5% ) Of the last full-term pregnancy, of which 72 cases of singleton pregnancies, 48 ​​cases of multiple pregnancies were induced by hMG ovulation and pregnancy, the patient spontaneously or induced menstrual cycle from the first 5 days of hMG15OU intramuscular injection, once daily, abdominal or vaginal ultrasound Monitoring follicular development, hCGS000U intramuscularly when there are one or more follicles> 18mm in diameter, and an intercourse test prior to intramuscular hCG administration. Cervical mucus was scored according to the method of Insler et al. According to the evaluation of Swyer, the number of active spermatozoa in high power field was observed. The patients were not given progesterone. The plasma progesterone concentration was measured on day 7 of hCG withdrawal. RESULTS: Of the 192 pregnant women who induced ovulation with hMG and hCG500OU, the mean luteal plasma progesterone concentration was 29. O7ng / ml, full-term single-boat pregnancy was 25.85us / ml, full-term multiple pregnancy was 31.49ng / ml, abortion was 2864ng / ml, ectopic pregnancy ZI. 54 ng / ml, and 41.39 ng / ml for preterm delivery (9/14 for multiple births). There was no significant difference between full-term delivery and abortion, but significant differences were found in single-and multiple-service pregnancies. P <0.5. The authors believe that the mid-luteal determination of plasma progesterone concentration is one of the best ways to determine ovulation and luteal function. Ovulation determination of the other party?
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