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目的探讨不孕不育与抗精子抗体(AsAb)的相关性。方法采用金标斑点渗滤法检测403例不孕不育患者血清中AsAb,并与对照组相比较。结果不孕不育组AsAb总阳性检出率为27.30%(110/403),女性不孕患者阳性率为27.84%(93/334),男性不育患者阳性率为24.64%(17/69),不孕不育组与对照组比较,差异有统计学意义(P<0.01)。结论 AsAb与不孕不育密切相关,检测血清AsAb有助于免疫性不孕不育的诊断。
Objective To investigate the relationship between infertility and antisperm antibody (AsAb). Methods AsAb in serum of 403 cases of infertility patients was detected by gold standard spot percolation method and compared with the control group. Results The positive rate of AsAb in infertility group was 27.30% (110/403), the positive rate in female infertility was 27.84% (93/334), and the positive rate in male infertility was 24.64% (17/69) , The infertility group and the control group, the difference was statistically significant (P <0.01). Conclusion AsAb is closely related to infertility, and detection of serum AsAb is helpful for the diagnosis of immune infertility.