Significant variations in alternative splicing patterns and expression profiles between human-mouse

• 作 者: Geng Chen Jiwei Chen Jianmin Y
• 机 构: TheCenterforBioinformaticsandComputationalBiology,CenterforPharmacogenomics,NationalCenterforToxicol
• 出 处: 中国科学：生命科学英文版
• 发表日期: 2017年2期
• 关键词: 同源基因 选择性剪接 早期胚胎 表达谱 小鼠 胚胎发育阶段 胚胎发育过程 生物学功能 ortholog alternative splicing RNA-s
• 基金项目: supported by the China Human Proteomics Project (2014DFB30010),,the National High Technology Research and Development Program of China (2015AA020104),,the National Natural Science Foundation of China

Human and mouse orthologs are expected to have similar biological functions; however, many discrepancies have also been reported. We systematically compared human and mouse orthologs in terms of alternative splicing patterns and expression profiles. Human