论文部分内容阅读
目的探讨血液透析联合药物治疗重症尿毒症的临床疗效。方法选取温岭市第一人民医院2013年2月—2016年1月收治的重症尿毒症患者130例,随机分为对照组和观察组,各65例。对照组患者给予血液透析治疗,观察组患者在对照组患者基础上给予葡萄糖酸钙治疗。比较两组患者临床疗效,治疗前后皮肤瘙痒评分及生活质量评分。结果观察组患者临床疗效优于对照组(P<0.05)。治疗前,两组患者皮肤瘙痒评分比较,差异无统计学意义(P>0.05);治疗后,观察组患者皮肤瘙痒评分低于对照组(P<0.05)。治疗前,两组患者物质生活状态、心理功能、社会功能、躯体功能评分比较,差异无统计学意义(P>0.05);治疗后,观察组患者物质生活状态、心理功能、社会功能、躯体功能评分高于对照组(P>0.05)。结论血液透析联合药物治疗重症尿毒症临床疗效确切,可有效改善患者皮肤瘙痒症状,提高生活质量。
Objective To investigate the clinical efficacy of hemodialysis combined with drugs in the treatment of severe uremia. Methods 130 cases of severe uremic patients admitted to the First People’s Hospital of Wenling from February 2013 to January 2016 were randomly divided into control group and observation group, with 65 cases in each group. Patients in the control group were treated with hemodialysis. Patients in the observation group were given calcium gluconate on the basis of the control group. The clinical efficacy, the pruritus score and the quality of life score before and after treatment were compared between the two groups. Results The clinical efficacy of the observation group was better than that of the control group (P <0.05). Before treatment, there was no significant difference in the pruritus scores between the two groups (P> 0.05). After treatment, the pruritus scores in the observation group were lower than those in the control group (P <0.05). Before treatment, there was no significant difference in material life status, psychological function, social function and physical function score between the two groups (P> 0.05). After treatment, the physical and psychological status, social function, body function Score higher than the control group (P> 0.05). Conclusion Hemodialysis combined with drug treatment of severe uremia clinical curative effect is exact, can effectively improve the skin pruritus in patients with symptoms, improve quality of life.