PSC-induced Galectin-1 Promotes the Malignant Behavior of Pancreatic Ductal Adenocarcinoma

• 作 者: Dong Tang Qi Wu Hong Peng Zhan
• 机 构: DepartmentofGeneralSurgery,DepartmentofClinicalMedicine,DepartmentofGeneralSurgery
• 出 处: 肿瘤营养学杂志(英文)
• 发表日期: 2019年3期
• 关键词: PANCREATIC DUCTAL ADENOCARCINOMA PANCREATIC stellate cells GALECTIN-1 INVASION M
• 基金项目: supported by grants from the National Natural Science Funding of China(No.81572344),the Training Project of Key Talents of Youth Medicine in Jiangsu province,China(No.QNRC2016330).

Background Galectin-1 is aβ-galactoside-binding protein overexpressed in the pancreatic stellate cells(PSCs)of pancreatic ductal adenocarcinoma(PDAC),while its expression is typically low in pancreatic cancer cells(PCCs).The point at which galectin-1 expr