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目的调查1例接种水痘疫苗发生过敏性休克的原因,总结并吸取经验教训。方法分析事件发生经过、处置及转归。结果综合患儿发病情况和临床表现(接种后5min出现哭闹、颜面潮红,继而呼吸困难、口唇发绀、面苍白、眼睑浮肿)、处置及转归(注射肾上腺素和吸氧,约5min后病情稳定),结合现场调查及患儿接种史,确诊为“预防接种致过敏性休克”。结论过敏性休克是常见的预防接种异常反应,受种者在接种地点留观30min及接种现场配备急救药械,是处置预防接种等异常反应的关键措施。
Objective To investigate the cause of anaphylactic shock in one case of vaccination with chickenpox, summarize and learn from the experience. Methods to analyze the incident after, disposal and outcome. Results The incidence of children and clinical manifestations (crying 5 minutes after inoculation, facial flushing, and then breathing difficulties, lips cyanosis, pale face, eyelid edema), treatment and prognosis (injection of epinephrine and oxygen, about 5min after the disease Stable), combined with field surveys and vaccination history, diagnosed as “vaccination caused by anaphylactic shock ”. Conclusions Anaphylactic shock is a common abnormal reaction of immunization. It is the key measure to deal with the abnormal reaction such as vaccination when the recipient is observed for 30 minutes at the inoculation site and equipped with emergency medical equipment at the vaccination site.