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检测35例急性病毒性乙型肝炎,36例肝硬化和28例原发性肝癌病人的血小板计数(PLT),平均血小板体积(MPV),血小板粘附试验(PAdT),二磷酸腺苷(ADP)诱导的血小板聚集试验(PAgT)以及血小板β-球蛋白(β-TG)释放功能等5项指标。结果:急性病毒性乙型肝炎组PLT、β-TG与对照组比较无显著性差异,但MPV、PAdT和PAgT显著高于对照组。肝硬化组和肝癌组PLT、MPV、PAdT和PAgT均显著低于对照组,两组之间无显著性差异。肝硬化β-TG显著高于对照组,肝癌组β-TG显著高于肝硬化组。肝细胞功能损害愈严重,以上各项指标偏离正常值愈远。经治疗肝细胞功能有所恢复后,以上各项指标也不同程度地趋近正常。
The platelet count (PLT), mean platelet volume (MPV), platelet adhesion test (PAdT) and adenosine diphosphate (ADP) in 35 patients with acute viral hepatitis B, 36 patients with cirrhosis and 28 patients with primary hepatocellular carcinoma ) Induced platelet aggregation test (PAgT) and platelet β-globulin (β-TG) release of five indicators. Results: There was no significant difference between PLT and β-TG in acute viral hepatitis B group and control group, but MPV, PAdT and PAgT were significantly higher than those in control group. The levels of PLT, MPV, PAdT and PAgT in cirrhosis and hepatocellular carcinoma were significantly lower than those in control group, with no significant difference between the two groups. Β-TG of liver cirrhosis was significantly higher than that of control group, β-TG of liver cancer group was significantly higher than that of cirrhosis group. Hepatocyte dysfunction more serious, the above indicators deviate from the normal farther. After the treatment of liver cell function has been restored, the above indicators are approaching normal to varying degrees.