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目的探讨上尿路梗阻伴发慢性非细菌性膀胱炎的诊治分析。方法回顾性分析137例上尿路梗阻住院病人伴发慢性非细菌性膀胱炎的临床资料,通过尿液培养、膀胱镜检查、活检等检查手段以及输尿管镜手术过程中确诊慢性非细菌性膀胱炎。结果 137例中发现慢性非细菌性膀胱炎32例(23.4%),这其中上尿路因结石梗阻出现的慢性非细菌性膀胱炎27例(19.7%),非结石因素梗阻原因出现的慢性非细菌性膀胱炎5例(3.6%)。32例非细菌性膀胱炎,腺性23例,增生性3例,膀胱白斑病变6例,合并慢性输尿管炎、输尿管息肉11例。在32例上尿路梗阻伴发非细菌性膀胱炎病例中,中段尿细菌培养阳性3例,均为大肠埃希氏杆菌,96例不伴有慢性膀胱炎病例中中段尿培养阳性者11例,大肠埃希氏杆菌10例,金葡菌和表皮葡萄球菌1例。6例上尿路梗阻伴发非细菌性膀胱炎病例予以随访3月,膀胱炎症病灶消失。结论上尿路梗阻情况下可伴发慢性非细菌性膀胱炎。
Objective To investigate the diagnosis and treatment of upper urinary tract obstruction associated with chronic non-bacterial cystitis. Methods A retrospective analysis of 137 cases of upper urinary tract obstruction in patients with chronic non-bacterial cystitis associated with clinical data through urine culture, cystoscopy, biopsy and other means of examination and ureteroscopic diagnosis of non-bacterial cystitis during surgery . Results Of the 137 cases, 32 cases (23.4%) of chronic non-bacterial cystitis were found. Of these, 27 cases (19.7%) of chronic non-bacterial cystitis caused by stone obstruction in the upper urinary tract, chronic non-stone obstruction Bacterial cystitis in 5 cases (3.6%). 32 cases of non-bacterial cystitis, 23 cases of glandular hyperplasia in 3 cases, 6 cases of bladder leukoplakia, chronic ureteral inflammation, ureteral polyps in 11 cases. Among the 32 cases of upper urinary tract obstruction associated with non-bacterial cystitis, the middle stage of urinary bacteria culture positive in 3 cases were Escherichia coli, 96 cases without chronic cystitis in the middle urine culture positive in 11 cases 10 cases of Escherichia coli, 1 case of Staphylococcus aureus and Staphylococcus epidermidis. Six cases of upper urinary tract obstruction associated with non-bacterial cystitis were followed up for 3 months, the lesions of the bladder inflammation disappeared. Conclusion Upper urinary tract obstruction may be associated with chronic non-bacterial cystitis.