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目的探讨川崎病临床诊断及其治疗。方法对2003年1月-2006年12月收治的50例川崎病的临床资料进行分析。结果男33例,女17例,～1岁7例,～3岁25例,3-5岁9例,>5岁9例。50例患儿中较为常见的表现依次是发热,口唇红、皲裂、杨梅舌88%,指、趾端脱皮及肛周脱皮80%,眼结膜充血74%,皮疹58%,颈淋巴结肿大54%,手足硬肿44%,心脏彩超检查50例,异常39例。典型川崎病42例,不典型8例。结论川崎病诊断标准5项指标不是同时出现。应动态观察,对不典型川崎病应常规做心脏超声检查。及早应用丙种球蛋白,对有效地控制冠脉损伤及预防冠状动脉瘤形成有重要意义。
Objective To investigate the clinical diagnosis and treatment of Kawasaki disease. Methods Clinical data of 50 patients with Kawasaki disease admitted from January 2003 to December 2006 were analyzed. Results There were 33 males and 17 females, 7 cases were 1 year old, 25 cases were 3 years old, 9 cases were 3-5 years old and 9 cases were> 5 years old. 50 cases of children are more common in the order of fever, lip red, chapped, 88% bayberry tongue, finger, toe and perianal peeling 80%, conjunctival hyperemia 74%, skin rash 58%, cervical lymph node enlargement 54 %, 44% of hand and foot sclerosis, 50 cases of cardiac ultrasonography, abnormal 39 cases. 42 cases of typical Kawasaki disease, atypical in 8 cases. Conclusions The five diagnostic criteria of Kawasaki disease do not appear at the same time. Should be dynamic observation, atypical Kawasaki disease should be routine to do cardiac ultrasound. The early application of gamma globulin can effectively control coronary artery injury and prevent the formation of coronary aneurysms.