【摘 要】
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Zwitterionic polymer materials have been extensively studied,but zwitterionic peptides supramolecular hydrogel materials are rarely studied.In this study,the preparation of two zwitterionic hydrogels using self-assembled peptides were reported.The hydroge
【机 构】
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State Key Laboratory of Medicinal Chemical Biology,Key Laboratory of Bioactive Materials,Ministry of
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Zwitterionic polymer materials have been extensively studied,but zwitterionic peptides supramolecular hydrogel materials are rarely studied.In this study,the preparation of two zwitterionic hydrogels using self-assembled peptides were reported.The hydrogels could be fabricated easily by changing the temper-ature or enzyme catalysis in a short time.And the differences in structure and function of the zwitterion peptide hydrogels caused by the two preparation methods were also be compared.We found that the hy-drogel prepared by enzyme induced self-assembly has better solubility and lower cytotoxicity than that prepared by the heating-cooling process.The result showed the enzyme induced self-assembly way to form zwitterionic peptides supramolecular hydrogel materials could have further biomedical applications.
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