论文部分内容阅读
目的观察重组甘精胰岛素联合阿卡波糖与预混胰岛素治疗2型糖尿病的疗效比较。方法将120例糖尿病患者随机分为治疗组和观察组,治疗组给予阿卡波糖150mg,3次/d服用,在此基础上每日睡前皮下注射一次重组甘精胰岛素;观察组给予预混胰岛素30R。两组的疗程均为12周。结果两组治疗后的空腹血糖(FBG)、餐后2h血糖(P2hBG)、糖化血红蛋白(HbAlc)水平与治疗前相比差异有统计学意义(P<0.05)。结论对于2型糖尿病患者注射重组甘精胰岛素联合口服降糖药的效果优于单纯注射预混胰岛素,其血糖达标时间短,而且更安全。
Objective To observe the efficacy of recombinant glargine combined with acarbose and premixed insulin in the treatment of type 2 diabetes mellitus. Methods 120 patients with diabetes mellitus were randomly divided into treatment group and observation group. The treatment group was given acarbose 150mg three times daily, on this basis, daily subcutaneous injection of recombinant insulin glargine once a day before bedtime; Mixed insulin 30R. The two groups were treated for 12 weeks. Results After treatment, fasting blood glucose (FBG), postprandial 2h blood glucose (HbA1c) and HbAlc levels were significantly different from those before treatment (P <0.05). Conclusion The effect of injecting recombinant glargine in combination with oral hypoglycemic agents on type 2 diabetes mellitus is better than that of premixed insulin alone, and its blood glucose is short and safe.