Studies on Macrocyclic Diterpenoids (Ⅵ)——A Novel Synthetic Route to (±)-Cembrene-A

• 作 者: 李卫东 李瀛 李裕林
• 机 构: StateKeyLaboratoryofAppliedOrganicChemistry,InstituteofOrganicChemistry,LanzhouUniversity,Lanzhou730
• 出 处: 中国科学：化学英文版
• 发表日期: 1993年10期
• 关键词: SYNTHESIS MACROCYCLIC DITERPENE (±)-cembrene-A (E E E)-4 8 12-trimethyl-1-i
• 基金项目: Project supported by the National Natural Science Foundation of China and by the Special Research Grant for Doctoral Sites in Universities.

The total synthesis of(土)-cembrene-A, a termite pheromone, was achieved from geranylacetone and geraniol as starting materials. The key steps were the phase transfer catalyzed coupling reaction of sulphone (6) with chloride (9) and the intramolecular macr