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目的探讨急性胰腺炎(AP)患者超敏C反应蛋白(hs-CRP)和嗜酸性粒细胞(EOS)的变化,并分析两者相关性。方法 AP组:南开医院的2013年1月-2015年8月的AP患者346例。对照组:100例同期本院健康体检者。检测hsCRP和EOS含量和百分比,并比较两组各种参数,相关性分析应用Pearson。结果 AP组hs-CRP显著高于对照组,差异有统计学意义(P<0.01),AP组EOS含量和百分比均低于对照组,差异有统计学意义(P<0.05);AP组hs-CRP与EOS含量及百分比呈负相关,差异有统计学意义(r=-0.161,P<0.05;r=-0.285,P<0.01)。结论 AP患者的hs-CRP升高,EOS含量和百分比降低;两者呈负相关;其相关性或能作为AP诊断和疗效观察的一个指标。
Objective To investigate the changes of hs-CRP and eosinophil (EOS) in patients with acute pancreatitis (AP) and to analyze their correlation. Methods AP group: 346 cases of AP patients from January 2013 to August 2015 in Nankai Hospital. Control group: 100 cases of the same period our hospital health examination. The contents and percentage of hsCRP and EOS were detected, and the two groups of parameters were compared. Pearson was used to analyze the correlation. Results The hs-CRP in AP group was significantly higher than that in control group (P <0.01). The content and percentage of EOS in AP group were lower than those in control group (P <0.05) CRP and EOS content and the percentage was negatively correlated, the difference was statistically significant (r = -0.161, P <0.05; r = -0.285, P <0.01). Conclusions Patients with AP have higher hs-CRP, lower EOS content and percentage, and are negatively correlated with each other. The correlation may serve as an index for the diagnosis and treatment of AP.