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日本森永乳业公司和美国 Genetics Institute(GI)公司都宣布成功地克隆化了有待查明其机理的血液增殖分化因子——人巨噬细胞集落刺激因子(M-CSF,CSF-1)的基因。M-CSF 是刺激巨噬细胞的前驱细胞,促进巨噬细胞增殖分化的因子。巨噬细胞是能吞食细菌和癌细胞等,并从体内排出的非特异性的免疫系统的主力,是活体防御的重要细胞。GI 公司开发 M-CSF 的目的是为了制造肺炎等感染症的治疗药,现在正进行临证前期试验,计划在1987年内进入临床试验。森永乳业公司是否要开发重组 M-CSF,现在似乎还没有决
Both Moriya Dairy Company and Genetics Institute (GI) have announced the successful cloning of the gene for human proliferative differentiation factor-human macrophage colony-stimulating factor (M-CSF, CSF-1) whose mechanism is to be clarified. M-CSF is a pro-inflammatory cell that stimulates macrophages and promotes the proliferation and differentiation of macrophages. Macrophages are the main cells of the nonspecific immune system that are capable of ingesting bacteria and cancer cells, etc., and are excreted from the body. They are important cells for living body defense. The purpose of GI Corporation’s development of M-CSF is to manufacture therapeutic drugs for infectious diseases such as pneumonia. Currently, preliminary trials are underway and planned to enter clinical trials in 1987. Morinaga dairy companies to develop recombinant M-CSF, it seems that no decision yet