论文部分内容阅读
目的:探讨宫颈癌患者术后放疗的疗效、并发症以及预后影响因素。方法:回顾性分析2006-01-01-2009-09-30在我科接受术后放疗的ⅠA～ⅡB期具有预后不良因素的232例宫颈癌患者。结果:3年总生存率、无瘤生存率和盆腔控制率分别为92.5%、89.2%和93.3%。无盆腔淋巴结转移者3年总生存率为93.2%,有盆腔淋巴结转移者为77.2%,差异有统计学意义,P=0.036。在外照射结束后接受腔内后装治疗和未接受后装治疗患者总生存率分别为96.6%和92.8%,盆腔控制率均为95.9%,差异无统计学意义,P值分别为0.183和0.519。结论:具有不良预后因素的宫颈癌患者接受术后放疗,可获得满意的总生存率、无瘤生存率和盆腔控制率,肿瘤远处转移为治疗失败主要原因。
Objective: To investigate the efficacy, complications and prognostic factors of postoperative radiotherapy for cervical cancer patients. Methods: A retrospective analysis of 232 cervical cancer patients with stage ⅠA ~ ⅡB adverse prognostic factors who received postoperative radiotherapy in our department from January 2006 to January 2009 was performed. Results: The overall 3-year survival rate, tumor-free survival rate and pelvic control rate were 92.5%, 89.2% and 93.3% respectively. The 3-year overall survival rate without pelvic lymph node metastasis was 93.2%, with pelvic lymph node metastasis 77.2%, the difference was statistically significant (P = 0.036). The total survival rate of patients receiving endovascular treatment with or without post-treatment after external irradiation was 96.6% and 92.8%, respectively. The pelvic control rate was 95.9%, with no significant difference (P = 0.183 and 0.519 respectively). CONCLUSIONS: Cervical cancer patients with unfavorable prognosis receive postoperative radiotherapy to obtain satisfactory overall survival rate, tumor-free survival rate and pelvic control rate. The distant metastasis of tumor is the main reason for the failure of treatment.