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患者女,35岁,因患有十二指肠溃疡3年,于1998年6月10日服用雷尼替丁1粒(150mg),30分钟后双耳、颈部奇痒,颈胸部出现皮疹并迅速向全身蔓延,皮肤蚁走样麻木、逐渐烦躁、心慌、胸闷、四肢乏力、神智不清、胡言乱语。来院急诊,查体:呈现谵妄状态,面色苍白,四肢冷,脉扪不清。颈、胸、腹、四肢广泛荨麻疹。心音低钝,心率每分钟 135次,血压52/0mmHg(7/0 kPa),呼吸急促,立即肌注肾上腺素1mg,静注50％葡萄糖注射液20ml加地塞米松10mg,静滴葡萄糖氯化钠注射液300ml加多巴胺150mg,0.5h后脉搏能扪清,皮肤复暖,血压105/71 mmHg,神志恢复,观察6h,血压稳定在112/
The patient, 35 years old, had duodenal ulcer for 3 years and took ranitidine 1 capsule (150 mg) on June 10, 1998. After 30 minutes, both ears, itchy neck and rash on neck and neck And quickly spread to the body, skin ants like numbness, and gradually irritability, palpitation, chest tightness, weakness, confusion, nonsense. To hospital emergency, physical examination: delirium, pale, limbs cold, pulse palpable. Neck, chest, abdomen, limbs extensive urticaria. Low heart rate, heart rate of 135 beats per minute, blood pressure 52 / 0mmHg (7 / kPa), shortness of breath, immediate intramuscular epinephrine 1mg, intravenous injection of 50% glucose 20ml plus dexamethasone 10mg, intravenous glucose and sodium chloride 300ml injection of dopamine 150mg, 0.5h after the pulse palpable clear skin warming, blood pressure 105/71 mmHg, consciousness recovery, observed 6h, blood pressure stabilized at 112 /