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目的探讨伽玛刀在不适合开放手术或经尿道电切术的高危前列腺增生患者治疗中的应用。方法采用深圳奥沃公司生产的OUR-QGD型立体定向全身伽玛刀治疗20例高危前列腺增生患者。应用国际前列腺症状评分(IPSS)、前列腺重量、最大尿流率(Qmax)、残余尿量作为评价指标。观察上述数据在治疗前后的改变及其临床意义。结果术后随访6个月,IPSS评分由治疗前29分降至19.6分(P<0.01)。前列腺重量平均值均由治疗前的(56.4±4.4)g减少至(54.8±4.3)g(P>0.05)。最大尿流率平均值由治疗前的(6.7±1.8)ml/s增加至(11.5±1.7)ml/s(P<0.01),残余尿量平均值由治疗前的(85.1±27.8)ml降至(50.9±15.6)ml(P<0.01)。结论立体定位体部伽玛刀治疗高危前列腺增生症患者具有简便、安全、无创、痛苦小、并发症少、疗效好,可不需住院等优点,对不愿意接受手术或不宜手术的高危前列腺增生患者不失为一种良好的治疗方法,但费用较高。
Objective To investigate the application of Gamma Knife in the treatment of high-risk benign prostatic hyperplasia patients who are not suitable for open surgery or transurethral resection of the prostate. Methods Twenty patients with benign prostatic hyperplasia (BPH) were treated with OUR-QGD stereotactic gamma knife made by Shenzhen Ovo Company. The International Prostate Symptom Score (IPSS), prostate weight, maximum flow rate (Qmax) and residual urine volume were used as the evaluation indexes. To observe the above data before and after treatment changes and their clinical significance. Results Six months after the operation, the IPSS score decreased from 29 points before treatment to 19.6 points (P <0.01). The average prostate weight decreased from (56.4 ± 4.4) g to (54.8 ± 4.3) g before treatment (P> 0.05). The mean maximum flow rate increased from (6.7 ± 1.8) ml / s to (11.5 ± 1.7) ml / s before treatment (P <0.01), and the average residual urine volume decreased from 85.1 ± 27.8 ml To (50.9 ± 15.6) ml (P <0.01). Conclusions Stereotactic gamma knife treatment of high-risk benign prostatic hyperplasia patients with simple, safe, noninvasive, less pain, fewer complications, good curative effect, may not need hospitalization, etc., unwilling to accept surgery or not suitable for high-risk patients with benign prostatic hyperplasia After all, a good treatment, but the cost is higher.