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为探讨尿毒症患者丙型肝炎病毒(HCV)感染的易感性。采用逆转录聚合酶链反应(RTPCR)技术检测血清HCV-RNA。结果:90例患者中42例HCV-RNA阳性,48例HCV-RNA阴性,HCV感染率为46.7%(42/90),其中输血患者HCV感染率为64.3%(27/42),非输血患者为31.3%(15/48),血透患者HCV感染率为42.9%(9/21),腹透患者为22.2%(6/27)。结果表明:尿毒症患者HCV感染与输血、透析方式等有关,而与乙肝病毒感染无明显关系。
To investigate the susceptibility of hepatitis C virus (HCV) infection in patients with uremia. Serum HCV-RNA was detected by reverse transcription-polymerase chain reaction (RTPCR). Results: Of the 90 patients, 42 were positive for HCV-RNA, 48 were negative for HCV-RNA, and the HCV infection rate was 46.7% (42/90). The HCV infection rate in transfused patients was 64.3% (27/42) , 31.3% (15/48) in non-transfusion patients, 42.9% (9/21) in hemodialysis patients and 22.2% (6/27) in peritoneal dialysis patients. The results showed that: HCV infection in patients with uremia and blood transfusion, dialysis, etc., but no significant relationship with hepatitis B virus infection.