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目的 就性别对心率 (HR)调整心电图ST段降低方法诊断冠心病的影响进行探讨。方法 选取可疑冠心病患者共 173例 ,测定运动试验过程中心电图ST段变化值及ST/HR斜率和ST/HR指数 ,以冠状动脉 (冠脉 )造影结果作为诊断冠心病的标准。结果 ST/HR斜率和ST/HR指数诊断冠心病的敏感性、特异性均明显高于传统ST段指标 (P <0 0 5 )。ST/HR斜率和ST/HR指数诊断冠心病的敏感性男性患者分别提高 2 3%和 16 % ,女性患者分别提高 5 0 %和 4 2 % ,差异均有显著性意义 (P <0 0 5 ) ;而ST/HR斜率和ST/HR指数诊断冠心病的特异性 ,男性患者无明显提高 (P >0 0 5 ) ,女性患者分别提高 5 8%和 5 0 % (P <0 0 5 )。结论 ST/HR斜率和ST/HR指数与传统ST段指标相比 ,女性患者诊断冠心病的敏感性和特异性明显提高 ,男性患者敏感性有提高 ,特异性无明显变化
Objective To investigate the influence of gender on the adjustment of heart rate (HR) to adjust the ST segment depression of ECG in the diagnosis of coronary heart disease. Methods A total of 173 patients with suspected CHD were enrolled in this study. Changes of ST segment and ST / HR slope and ST / HR index of electrocardiogram during exercise test were measured. Coronary artery (coronary) angiography was used as the standard for diagnosis of coronary heart disease. Results The sensitivity and specificity of ST / HR slope and ST / HR index in diagnosing CHD were significantly higher than those of the traditional ST segment (P <0.05). The ST / HR slope and ST / HR index increased the sensitivity of coronary heart disease by 23% and 16% in male patients and 50% and 42% in female patients, respectively, with significant differences (P <0.05 ). The specificity of ST / HR slope and ST / HR index in the diagnosis of coronary heart disease was not significantly higher in males (P> 0.05) and in females by 58% and 50%, respectively (P <0.05) . Conclusion ST / HR slope and ST / HR index compared with the traditional ST-segment indicators, the sensitivity and specificity of female patients in the diagnosis of coronary heart disease was significantly increased, the sensitivity of male patients increased, the specificity of no significant change