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目的探讨阳江高本底辐射调查地区居民鼻咽癌的相关危险因素，为正确评价高本底辐射致癌危险提供基础。方法选择固定队列中１９８７～１９９５年间鼻咽癌死亡病例作为研究对象，随机选择对照，１∶２配对。研究的因素包括职业、文化程度、居住史与生活环境等一般社会经济状况，农药使用，吸烟、饮酒、饮食、医用Ｘ射线照射和鼻咽癌家族史等。资料收集采用面访方式。资料采用条件Ｌｏｇｉｓｔｉｃ回归分析，计算比数比（ＯＲ）及相应的９５％置信区间和Ｐ值。结果有效访问了１０２例病例和２０２例对照。单因素Ｌｏｇｉｓｔｉｃ回归分析发现，经常摄入咸鱼、咸菜、豆豉和腊肉，慢性鼻炎史，家族鼻咽癌史等因素与鼻咽癌有显著性关联；多因素Ｌｏｇｉｓｔｉｃ回归分析的结果显示，经常摄入咸鱼，慢性鼻炎史和家族鼻咽癌史是鼻咽癌独立的危险因素；在控制某些因素后，引入高本底辐射，吃咸鱼和豆豉，吸烟和饮酒等因素进行多因素Ｌｏｇｉｓｔｉｃ回归分析，结果显示吃咸鱼为鼻咽癌发病唯一危险因素（ＯＲ＝２．８，９５％ＣＩ：１．５２～５．１８）；吸烟（ＯＲ＝１．２，９５％ＣＩ：０．６５～２．２２）、饮酒（ＯＲ＝０．８３，９５％ＣＩ：０．３８～１．７８）和高本底辐射（ＯＲ＝０．８６，９５％Ｃ?
Objective To investigate the related risk factors of nasopharyngeal carcinoma in residents surveyed by high background radiation in Yangjiang area and provide the basis for correctly evaluating the carcinogenic risk of high background radiation. Methods The deaths of NPC from 1987 to 1995 in the fixed cohort were selected as the research subjects, and the controls were randomly selected and matched with 1: 2. The factors studied include general socioeconomic status such as occupation, educational level, residence history and living environment, use of pesticides, smoking, drinking, diet, medical X-ray and family history of NPC. Data collection using interview. Logistic regression analysis was used to calculate odds ratio (OR) and the corresponding 95% confidence intervals and P values. Results Effective access to 102 cases and 202 controls. Logistic regression analysis showed that frequent intake of salted fish, pickles, beans and bacon, history of chronic rhinitis, family history of nasopharyngeal carcinoma and other factors have a significant correlation with nasopharyngeal carcinoma; multivariate logistic regression analysis showed that frequent Into the salted fish, history of chronic rhinitis and family history of nasopharyngeal carcinoma nasopharyngeal carcinoma independent risk factors; after controlling for some factors, the introduction of high background radiation, eating salted fish and bean curd, smoking and drinking factors such as multivariate Logistic Regression analysis showed that eating salted fish was the only risk factor for the development of NPC (OR = 2.8,95% CI: 1.52-5.18); smoking (OR = 1.2,95% CI: (OR = 0.83, 95% CI: 0.38-1.78) and high background radiation (OR = 0.86, 95% C?