伽玛刀治疗小脑发育不良性神经节细胞瘤2例报告

• 作 者: 吴盛荣 何平
• 机 构: 重庆市解放军第三二四医院伽玛刀科,
• 出 处: 立体定向和功能性神经外科杂志
• 发表日期: 2014年04期
• 关键词: 伽玛刀治疗 伽玛刀 小脑 加权像 等信号 脑发育 条纹状 临床影像学 病灶体积 中心剂量

目的探讨小脑发育不良性神经节细胞瘤(又称为Lhermitte-Duclos dise,LLD)的临床影像学表现、诊断、伽玛刀治疗。方法分析伽玛刀治疗LLD的临床资料及随访复查资料。结果 LLD的MRI影像呈:沿小脑沟回走行的T1低信号、T2高信号和等信号交替的条纹状分层结构,病灶无强化,病理可确诊,首选手术治疗,伽玛刀治疗后病灶体积缩小,条纹状分层结构影变淡紊乱,能有效控制病情。结论 LLD临床极少见,缺乏临床特征,T2加权像可以诊断,伽玛刀治疗有效。

Objective To investigate the clinical imaging manifestations, diagnosis and gamma knife therapy of cerebellar dysplastic ganglioneuroma (also known as Lhermitte-Duclos disease, LLD). Methods The clinical data and follow-up data of gamma knife radiosurgery for LLD were analyzed. Results The MRI findings of LLD were: T1 low signal, T2 high signal and equal signal alternating striped striation along the cerebellar gyrus, no enhancement of the lesion, pathological diagnosis, preferred surgical treatment, lesion volume after gamma knife treatment Narrow, stripe-like layered structure pale disorder, can effectively control the disease. Conclusion LLD clinical rare, lack of clinical features, T2-weighted images can be diagnosed, gamma knife treatment is effective.