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细菌耐药性的发生原理及常见致病茵的耐药变迁情况细菌在体内外均可对抗菌素产生耐药性,体外经诱导而产生的耐药性常远较体内所能达到者为高。细菌对化学结构或作用原理相似的抗菌素间可发生程度不同的交叉耐药现象。细菌耐药性的发生原理细菌的耐药性主要由适应和突变两种方式形成,并可借转导、接合、转化等途径由耐药菌将耐药性转授给敏感菌。一、适应:适应是细菌产生耐药性的最主要方式。细菌为了求生存而发挥其适应功能,产生了能破
The principle of bacterial resistance and common pathogenic changes of drug resistance of bacteria in vitro and in vivo antibiotics can produce resistance, in vitro induced by the resulting resistance is often far higher than the body can be achieved. Bacteria can have different degrees of cross-resistance to antibiotics that have similar chemical structure or action. Bacterial drug resistance principle Bacterial drug resistance mainly by the adaptation and mutation in two ways to form, and by transduction, conjugation, transformation and other means by the resistant bacteria will be transferred to the susceptible strains. First, to adapt: Adaptation is the most important way for bacteria to produce drug resistance. Bacteria in order to survive and play its adaptation function, produced a broken