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目的:探讨静脉注射胺碘酮治疗室性心动过速的疗效。方法:心电图诊断为室性心动过速47例,给予胺碘酮3～5mg/kg稀释后10min缓慢静脉注射。如果无效,再重复1～2次,总量不超过10mg/kg。如果血液动力学不稳定,立即给予电复律,如果血液动力学稳定或已转为窦性心律,继以1mg/min,6h静脉滴注。6h后改为0.5mg/min,维持18h。以后改为口服胺碘酮。结果:成功复律39例,总有效率为82.9%;6例因不能转为窦性心律,后使用同步电击复律成功;1例因胺碘酮及电击复律均不成功,最后转为心室颤动死亡;1例发生尖端扭转性室速,给予异丙肾上腺素抢救成功。结论:静脉注射胺碘酮是治疗室性心动过速有效的药物之一。
Objective: To investigate the efficacy of intravenous amiodarone in the treatment of ventricular tachycardia. Methods: 47 cases were diagnosed as ventricular tachycardia by intravenous injection of amiodarone 3 ~ 5mg / kg diluted 10min after intravenous injection. If invalid, repeat 1 ~ 2 times, the total does not exceed 10mg / kg. If haemodynamic instability, immediate cardioversion, if the hemodynamic stability or has been converted to sinus rhythm, followed by 1mg / min, 6h intravenous infusion. After 6h changed to 0.5mg / min, maintained 18h. Later changed to oral amiodarone. Results: The success of cardioversion in 39 cases, the total effective rate was 82.9%; 6 cases can not be converted to sinus rhythm, the use of synchronous shock cardioversion success; 1 case due to amiodarone and electric cardioversion were unsuccessful, and finally turned Ventricular fibrillation death; 1 case of torsades de pointes occurred, given isoproterenol rescue success. Conclusion: Intravenous amiodarone is one of the effective drugs in the treatment of ventricular tachycardia.