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目的 通过对小气道疾病患者进行呼气相CT扫描 ,结合吸气相CT扫描 ,评价呼气相CT在诊断小气道疾病方面的应用价值。方法 对 3 1例小气道疾病患者及对照组 12例 ,使用螺旋CT进行呼气末的胸部CT扫描 ,结合吸气末CT扫描 ,测量和计算肺横断面积衰减分数 (CLARS) ,肺密度衰减值 (LDAV)。同时 ,对 2组分别进行了吸气末和呼气末的高分辨率扫描 (HRCT) ,重点观察呼气末的空气潴留征象。结果 病例组和对照组的横断面积衰减分数分别为 2 5和 48,肺密度衰减值分别为 79HU和 186HU ,2组结果有显著统计学差异。在呼气相HRCT扫描时观察空气潴留征象 (airtrapping) ,正常对照组中没有见到此征象 ( 0 % ) ,而 3 1例病例组中有 13例 ( 4 2 % )可见到空气潴留。结论 呼气相CT能够观察空气潴留征象 ,结合吸气相CT扫描 ,测量和计算CLARS、LDAV等指标 ,对小气道疾病的早期诊断和定量有较大的帮助 ,是一种有发展前途的检查方法
Objective To evaluate the value of expiratory CT in the diagnosis of small airway diseases through the expiratory phase CT scan of patients with small airway diseases combined with inspiration CT scan. Methods Thirty-one patients with small airway disease and 12 healthy controls were enrolled in this study. CT end-expiratory CT scan was performed with helical CT. The end-expiratory CT scan was used to measure and calculate the lung radiofrequency ablation fraction (CLARS) (LDAV). At the same time, high resolution scan (HRCT) of end-inspiratory and end expiratory were performed on the two groups, and the signs of air exhaustion at the end of expiration were observed. Results The attenuation scores of the cross-sectional area of cases and controls were 25 and 48, respectively. The attenuation values of lung density were 79HU and 186HU, respectively. There was significant difference between the two groups. Air-exhaustion airtrapping was observed during the expiratory HRCT scan, which was not seen in the normal control group (0%), whereas air retention was seen in 13 (42%) of the 31 cases. Conclusion The expiration phase CT can observe the signs of air retention. Combined with inspiration CT scan, the measurement and calculation of indicators such as CLARS and LDAV, it is of great help to the early diagnosis and quantification of small airway diseases. It is a promising test method