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以往的研究表明,柠檬酸铝(简称柠铝)有明显抑制实验性矽肺纤维化的作用,经柠铝治疗的矽肺病人,自觉症状多有不同程度的改善,且柠铝有毒性低、疗效稳定等优点,是一种较有前途的矽肺防治药物。但是,目前关于柠铝防治矽肺的作用机理尚不十分清楚。根据巨噬细胞吞噬二氧化硅粉尘后的崩解是矽肺发病过程中的首要环节的理论,本研究应用组织
Previous studies have shown that aluminum citrate (hereinafter referred to as lemon aluminum) significantly inhibited the experimental role of silicosis, the treatment of silicosis patients with aluminum, the symptoms have more or less improved, and the low toxicity of aluminum and aluminum, the efficacy of stable Etc., is a more promising silicosis prevention and treatment drugs. However, the current mechanism of the prevention and treatment of silicosis of limonite is not yet clear. According to macrophage phagocytosis of silica dust after the collapse of the pathogenesis of silicosis is the primary link in the theory, the application of tissue