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目的观察胺碘酮治疗冠心病合并室性心律患者的临床疗效。方法 50例冠心病合并室性心律失常患者在在改善心脏供血的前提下,口服胺碘酮治疗,主要根据24 h动态心电检查的结果判定疗效。结果 50例患者中29例心电图ST-T明显改善,19例心电图ST-T无明显改善,该组患者(VPC)36例有效率76%,3例室速被终止,且心绞痛症状迅速改善,窦性心律者的HR自(97.55±14.43)次/min减至(62.50±9.25)次/min,P<0.01,QTc自(410±41)min增至(525±76)min,P<0.01。结论胺碘酮在治疗冠心病合并室性心律失常中起到了良好效果。
Objective To observe the clinical efficacy of amiodarone in patients with coronary heart disease complicated with ventricular arrhythmias. Methods Fifty patients with coronary heart disease complicated with ventricular arrhythmia were treated with oral amiodarone under the premise of improving blood supply to the heart. The curative effect was mainly determined by the results of 24-hour ambulatory ECG examination. Results The electrocardiogram ST-T of 29 patients was significantly improved in 50 patients. There was no significant improvement in ST-T of 19 patients. The response rate of 36 patients in VPC group was 76%, and the ventricular tachycardia was terminated in 3 patients. The symptoms of angina improved rapidly, The HR of sinus rhythm decreased from (97.55 ± 14.43) / min to (62.50 ± 9.25) min / min, P <0.01, and the QTc increased from (410 ± 41) min to (525 ± 76) min, P <0.01 . Conclusion Amiodarone has a good effect in the treatment of coronary heart disease with ventricular arrhythmia.