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目的:评估甲状腺癌高频声像图中钙化的意义。方法:对271例甲状腺结节的高频声像图进行回顾性分析, 将其中的钙化分为三种类型: (1) 微钙化; (2) 粗钙化; (3) 弧形钙化。结果: 144例恶性组中, 检出钙化62例 (43.06% ), 其中微钙化46 例, 粗钙化16 例, 有微钙化的甲状腺癌中37例为乳头状癌。127例良性组中, 检出钙化11例(8.67% ), 微钙化5 例, 粗钙化5例, 弧形钙化1 例。两组钙化率有显著性差异。但粗钙化与微钙化在两组中无显著性差异。钙化在甲状腺癌诊断中的敏感性和特异性分别为43.06% 及91.33% 。结论: 高频声像图中的钙化是诊断甲状腺癌的一个特异性指标。钙化的形状对甲状腺结节的良恶性鉴别帮助不大,而微钙化是乳头状癌的一个特征性表现。
OBJECTIVE: To evaluate the significance of calcification in high-frequency sonograms of thyroid cancer. METHODS: A retrospective analysis was performed of 271 sonograms of thyroid nodules and the calcifications were divided into three types: (1) microcalcification; (2) coarse calcification; (3) arc calcification. RESULTS: Of the 144 malignant groups, 62 (43.06%) were found to be calcified, of which 46 cases were microcalcified, 16 cases were coarse calcified, and 37 cases of microcalcified thyroid cancer were papillary. Of the 127 benign groups, 11 (8.67%) were calcified, 5 were microcalcified, 5 were coarse calcified, and 1 was calcified. There was a significant difference in calcification rates between the two groups. However, there was no significant difference between the two groups in coarse calcification and microcalcification. The sensitivity and specificity of calcification in the diagnosis of thyroid cancer were 43.06% and 91.33%, respectively. Conclusion: Calcification in high-frequency acoustic imaging is a specific indicator for the diagnosis of thyroid cancer. The calcification shape does not help the differential diagnosis of benign and malignant thyroid nodules, and microcalcification is a characteristic manifestation of papillary carcinoma.