Role of adipose-derived stromal cells in pedicle skin flap survival in experimental animal models

• 作 者: Pericles Foroglou Vasileios Karathanasis Efterpi Demiri George Koliakos Marios Papadakis
• 机 构: Department of Plastic Surgery, Papageorgiou General Hospital,Aristotle University of Thessaloniki,De
• 出 处: World Journal of Stem Cells
• 发表日期: 2016年03期
• 关键词: adipose essentially starting defects viability have preferred appearance regener

The use of skin flaps in reconstructive surgery is the first-line surgical treatment for the reconstruction of skin defects and is essentially considered the starting point of plastic surgery. Despite their excellent usability, their application includes general surgical risks or possible complications, the primary and most common is necrosis of the flap. To improve flap survival, researchers have used different methods, including the use of adiposederived stem cells, with significant positive results. In our research we will report the use of adipose-derived stem cells in pedicle skin flap survival based on current literature on various experimental models in animals.

The use of skin flaps in reconstructive surgery is the first-line surgical treatment for the reconstruction of skin injury and is essentially considered the starting point of plastic surgery. Despite their excellent usability, their application includes general surgical risks or possible complications, the primary and researchers have used different methods, including the use of adipose derived stem cells, with significant positive results. In our research we will report the use of adipose-derived stem cells in pedicle skin flap survival based on current literature on various experimental models in animals.