Anti-inflammatory effect of cannabinoid agonist WIN55, 212 on mouse experimental colitis is related

• 作 者: Ya-Jing Feng Yong-Yu Li Xu-Hon
• 机 构: DepartmentofPathophysiology,DepartmentofCenterICU
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2016年43期
• 关键词: 煽动性的肠疾病 内长的 cannabinoid 系统 P38MAPK 试验性的大肠炎 CLAUDIN-1 Inflammatory bowel disease
• 基金项目: Supported by the National Natural Science Foundation of China,No.81400581(to Feng YJ) and No.81270477(to Li YY)

AIM To investigate the anti-inflammatory effect and the possible mechanisms of an agonist of cannabinoid(CB) receptors, WIN55-212-2(WIN55), in mice with experimental colitis, so as to supply experimental evidence for its clinical use in future. METHODS We