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目的:观察自拟平喘顺气汤联合沙丁胺醇雾化吸入治疗小儿慢性支气管炎的临床效果。方法:将92例患儿随机分为2组,对照组46例予沙丁胺醇雾化吸入治疗,观察组46例在对照组基础上加用自拟平喘顺气汤治疗。2组疗程均为7天,观察治疗后临床疗效、症状改善时间及血免疫球蛋白变化。结果:总有效率观察组为97.83%,对照组为86.96%,2组比较,差异有统计学意义(P<0.05)。治疗后观察组发热、咳嗽及肺部湿啰音消失时间均较对照组短,差异有统计学意义(P<0.05)。治疗后2组lg A、lg G、lg M水平均较治疗前上升(P<0.05);且治疗组上述指标改善优于对照组(P<0.05)。治疗期间2组均无不良反应发生。结论:平喘顺气汤结合沙丁胺醇雾化吸入治疗,能够快速改善患儿症状体征,提高机体免疫力,临床疗效显著。
Objective: To observe the clinical efficacy of self-made Pingchuan Shun Qi combined with salbutamol inhalation in the treatment of children with chronic bronchitis. Methods: Ninety-two children were randomly divided into two groups. 46 patients in the control group were given salbutamol inhalation. 46 patients in the observation group were treated with Pingchuan Shunqi Decoction on the basis of the control group. The two courses of treatment were 7 days, observed after treatment, clinical efficacy, improvement of symptoms and blood immunoglobulin changes. Results: The total effective rate was 97.83% in the observation group and 86.96% in the control group. There was significant difference between the two groups (P <0.05). After treatment, fever, cough and lung wet rales disappeared in the observation group compared with the control group, the difference was statistically significant (P <0.05). The levels of lg A, lg G and lg M in the two groups after treatment were all significantly higher than those before treatment (P <0.05). The improvement of the above indexes in the treatment group was better than that in the control group (P <0.05). No adverse reactions occurred in the two groups during the treatment. Conclusion: The combination of asthma and asthma soup combined with salbutamol inhalation therapy can quickly improve children’s symptoms and signs and improve immunity, with significant clinical efficacy.