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青霉素大量静点致白细胞减少较少见,我院住院病人中先后发现二例报告如下。 [例1]患者:男,55岁。支气管哮喘而入院,既往有慢性支气管炎、肺气肿。入院时白细胞10×10~9/L,中性76％。给予青霉素560万U静点,口服复方茶碱片。用药后的15d发现白细胞降到0.8×10~8/L、中性20％,立即停药,改用红霉素、地塞米松,静点。停青霉素后的d2、d3、d6,白细胞及中性分别为2×10~9/L,中性57％,4×10~9/L,中性60％,10×10~9/L,中性71％,血象完全恢复正常。 [例2]患者:男,49岁。腰痛,尿频,尿痛,白细胞9.6×10~9/L,中性70％,尿蛋
A large number of intravenous penicillin leukopenia less common in our hospital patients have found two cases reported as follows. [Example 1] Patient: Male, 55 years old. Bronchial asthma and admission, previous chronic bronchitis, emphysema. Admission leukocytes 10 × 10 ~ 9 / L, 76% of neutral. Give penicillin 5.6 million U static point, oral compound theophylline tablets. Fifteen days after treatment, leukocytes were found to be reduced to 0.8 × 10 -8 / L and neutral 20%. Immediate withdrawal was used instead of erythromycin, dexamethasone and intravenous injection. After stopping penicillin d2, d3, d6, white blood cells and neutrophils were 2 × 10 ~ 9 / L, neutral 57%, 4 × 10 ~ 9 / L, neutral 60%, 10 × 10 ~ 9 / L, Neutral 71%, blood completely returned to normal. [Example 2] Patient: Male, 49 years old. Low back pain, frequent urination, dysuria, leukocyte 9.6 × 10 ~ 9 / L, neutral 70%, urine egg