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大量的体外和动物实验均证明γ-干扰素具有免疫调节和抗纤维增生的作用[1] ,但γ-干扰素对持续免疫损伤性肝纤维化的治疗效果如何?目前国内尚未见相关报道。本研究利用异种动物血清诱导大鼠肝纤维化,再给予上海克隆生物高技术有限公司的重组γ-干扰素(商品名克隆伽玛) ,观察人
A large number of in vitro and animal experiments have shown that γ-interferon has immunomodulatory and anti-fibrotic effects [1], but γ interferon on the continuous immunocompromised liver fibrosis treatment effect? Currently no relevant reports. In this study, different animal serum was used to induce hepatic fibrosis in rats. Recombinant gamma interferon (trade name clone gamma) of Shanghai Clone Biotechnology Co., Ltd. was also given to the observer